Description:Mouse monoclonal antibody to human Factor IX

Purification:Protein G affinity purified

Product Type: Primary antibody

Target Protein:Human Factor IX

Immunogen:Human Factor IX

Fusion Myeloma:Sp2/0-Ag14

Specificity:Reactive to human Factor IX

Species Reacitvity:Human, others not tested

Host / Isotype:Mouse, IgG1 Kappa

Formulation:Lyophilized from a solution in 0.01M PBS, pH 7.2

Reconstitution:Double distilled water is recommended to adjust the final concentration to 1.00mg/mL.

Storage: Store at -20^oC

Research Area:Hematology, blood coagulation

Background:

Factor IX is one of the key factors for blood coagulation. It can be transformed into a two-chained activated form (Factor IXa) by factors in both coagulation pathways: by Factor XIa of the contact pathway or by Factor VIIa of the tissue factor pathway. In the presence of Factor VII cofactor, Ca++ and membrane phospholipids, Factor IXa activates Factor X. The activated Factor X (Factor Xa) triggers the transformation of prothrombin to thrombin, thus results in blood coagulation. Hemophilia B is a disease caused by Factor IX deficiency.

Application: ELISA

References:

If research is published using this product, please inform Anogen in order to cite the reference on this datasheet. Anogen will provide one unit of product in the same category as gratitude.